Parry - Romberg syndrome is a rare disease characterized by a slow deterioration (atrophy), progressive skin and soft tissues of half of the face (atrophy, hemifacial), as a rule, remains. It is more common in women than men. If early changes usually involve a high tissue of the upper jaw (maxilla) or between the nose and upper lip corners (nasolabial) and then progresses to the corner of the mouth, around eyes, eyebrows, ears and neck. Can degrade the language, soft and fleshy parts of the sky, the gums and influences. Eyes and cheeks the affected side may be sunk and the hair may be white or fall out (alopecia). In addition, the skin overlying affected areas may be darker pigmented (hyperpigmentation) with, in some cases, areas of hyperpigmentation and non-pigmented skin (vitiligo). Parry - Romberg syndrome, neurological disorders, including seizures and severe pain attacks the face (trigeminal neuralgia) is connected. The disease usually begins between the ages of 5 to 15 years begins. Progress atrophy often it takes 10.20 years, and then the process appears stable phase. If the relevant muscles may atrophy and bone loss may be the bones. The problem with the retina and optic nerve can occur, which surrounds the eye disease.
Is there any treatment?
There is no cure and no treatment that can progress Parry - Romberg syndrome is rest on our laurels. Or microvascular reconstructive surgery may be needed to repair tissue to die. Surgical intervention is generally agreed the best course of fatigue after completion of the disease and as growth. Most surgeons will wait a year or two before you start to reconstruction can be recommended. Muscle or bone grafts may also be helpful. Other symptomatic and supportive treatment.
What are the forecasts?
The prognosis for people with Parry - Romberg syndrome varies. In some cases, ends up full of atrophy influences. In mild cases, usually does not lead to disability, illness of other cosmetic effects.
What research is being done?
NINDS supports research on neurological disorders such as Parry - Romberg syndrome with a view to finding ways to prevent, treat and cure.
Is there any treatment?
There is no cure and no treatment that can progress Parry - Romberg syndrome is rest on our laurels. Or microvascular reconstructive surgery may be needed to repair tissue to die. Surgical intervention is generally agreed the best course of fatigue after completion of the disease and as growth. Most surgeons will wait a year or two before you start to reconstruction can be recommended. Muscle or bone grafts may also be helpful. Other symptomatic and supportive treatment.
What are the forecasts?
The prognosis for people with Parry - Romberg syndrome varies. In some cases, ends up full of atrophy influences. In mild cases, usually does not lead to disability, illness of other cosmetic effects.
What research is being done?
NINDS supports research on neurological disorders such as Parry - Romberg syndrome with a view to finding ways to prevent, treat and cure.
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